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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKACA
All Species:
35.76
Human Site:
S110
Identified Species:
71.52
UniProt:
P17612
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17612
NP_002721.1
351
40590
S110
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Chimpanzee
Pan troglodytes
XP_001171437
427
49115
S186
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Rhesus Macaque
Macaca mulatta
O62846
209
24077
Dog
Lupus familis
XP_867543
351
40605
S110
F
L
V
R
L
E
Y
S
F
K
D
N
S
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P05132
351
40552
S110
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Rat
Rattus norvegicus
P27791
351
40601
S110
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422379
398
45968
S157
F
L
V
K
L
E
Y
S
F
K
D
N
S
N
L
Frog
Xenopus laevis
Q6GPN6
434
49096
S168
F
L
V
G
L
H
F
S
F
Q
T
T
S
R
L
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
S167
F
L
V
G
L
H
Y
S
F
Q
T
T
D
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12370
353
40820
H112
F
L
V
S
L
R
Y
H
F
K
D
N
S
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P21137
404
46327
S147
F
L
V
N
M
T
F
S
F
K
D
N
S
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
T136
F
L
I
R
M
W
G
T
F
Q
D
A
R
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
51.2
93.1
N.A.
98
98
N.A.
N.A.
81.4
35.2
34.8
N.A.
82.4
N.A.
68.5
N.A.
Protein Similarity:
100
81.9
56.7
95.4
N.A.
99.4
99.1
N.A.
N.A.
84.6
54.1
53.1
N.A.
90
N.A.
78.4
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
100
100
N.A.
N.A.
93.3
60
46.6
N.A.
73.3
N.A.
80
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
66.6
60
N.A.
80
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
75
0
9
0
0
% D
% Glu:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
92
0
0
0
0
0
50
0
92
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
42
0
0
0
0
0
67
0
0
0
9
0
% K
% Leu:
0
92
0
0
75
0
0
0
0
0
0
0
0
0
84
% L
% Met:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
67
0
75
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
9
0
0
0
0
0
0
9
9
0
% R
% Ser:
0
0
0
9
0
0
0
75
0
0
0
0
75
0
0
% S
% Thr:
0
0
0
0
0
9
0
9
0
0
17
17
0
0
0
% T
% Val:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _